Independent and joint associations of hypertension and depression with cardiovascular diseases and all-cause mortality: a population-based cohort study.

ABSTRACT: Hypertension frequently co-exists with depression, leading to adverse health outcomes. This study aimed to examine the individual and joint effects of hypertension and depression on the risks of new-onset cardiovascular disease (CVD) and all-cause mortality among the middle-aged and older Chinese individuals. Data from the China Health and Retirement Longitudinal Study (CHARLS) during 2011-2020 were used. Participants were divided into four groups for comparison: hypertension alone, depression alone, both conditions, neither condition. Multivariate logistic regression models were established to compare the risks of all-cause mortality and CVD among the four groups. A total of 9178 participants without pre-existing CVD were included and followed for nine years. Compared with individuals wit

SUBMITTER: Tu Q 

PROVIDER: S-EPMC12417204 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature