Influence of a defoaming agent - simethicone - on endoscope cleaning and disinfection: Prospective real-world study.

ABSTRACT:

Background and study aims

Simethicone has been extensively utilized in endoscopy examinations and therapies; however, consensus regarding its impact on endoscopy cleaning is still lacking. The aim of this study was to assess impact of simethicone use during endoscopic examination on efficacy of endoscope cleaning.

Methods

This was a prospective real-world study that involved use of varying concentrations of simethicone in the endoscope biopsy channel and auxiliary water channel.

Results

All simethicone residual amounts and adenosine triphosphate (ATP) values were analyzed every month for 1 year. Use of 1% and 2% concentrations of simethicone generally resulted in variations in residual simethicone levels between the two channels. There was no significant alteration in

SUBMITTER: Huang J 

PROVIDER: S-EPMC12417768 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature