Intragastric balloon for obesity treatment: Systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background and study aims

Intragastric balloon (IGB) is a minimally invasive and reversible endoscopic option for treating obesity. This systematic review and meta-analysis compared the effectiveness of IGB versus standard medical therapy (SMT) for obesity management, including studies with a minimum treatment duration of 6 months. Subgroup analyses were performed based on IGB type, baseline mean body mass index (BMI), and use of pharmacological therapy in the SMT group.

Methods

We searched for randomized controlled trials (RCTs) in MEDLINE, EMBASE, and Cochrane Library databases. Outcomes were evaluated at 6, 9, and 12 months after initiation of treatment. A random-effects model was used to calculate the pooled mean difference (MD) with 95% confidence interval (CI) for cont

SUBMITTER: Amaral GO 

PROVIDER: S-EPMC12417771 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature