Differentiation of tumor versus peritumoral cortex in gliomas by intraoperative electrocorticography.

ABSTRACT:

Background

Brain diffuse gliomas are highly epileptic and infiltrative tumors. Glioma surgery consists of the resection of the tumor core and the maximum of the peritumoral zone, infiltrated by tumor cells, guided by the intraoperative assessment of brain functionality and connectivity. However, its electrophysiological characteristics are poorly characterized.

Methods

We studied the characteristics of electrocorticographic (ECoG) signals, in the context of glioma surgery in awake conditions on 29 patients, using EEG activity sampled on the tumor itself versus on its borders and in healthy areas. We assessed the features of frequency bands and aperiodic components (offset and slope) of ECoG power spectra during awake glioma surgery, according to cortical tumoral versus perit

SUBMITTER: Diaz-Fernandez B 

PROVIDER: S-EPMC12417838 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature