Incidence and Sex-Based Comparison of Prosthesis-Patient Mismatch in Patients Undergoing Transcatheter Aortic Valve Replacement.

ABSTRACT:

Background

Prosthesis-patient mismatch (PPM) remains a topic of controversy in patients undergoing transcatheter aortic valve replacement (TAVR), particularly among women with smaller annuli. Although self-expanding valves (SEV) appear to provide superior hemodynamic performance than balloon-expandable valves, the impact of PPM severity on long-term survival, particularly regarding sex-specific differences, remains inadequately characterized.

Methods

This retrospective cohort study analyzed 3016 patients (1338 women) who underwent native valve TAVR from 2012 to 2021. Patients were stratified by sex, valve type (balloon-expandable valve vs SEV), and PPM predicted (PPM_P) and measured (PPM_M) severity as defined by the Valve Academic Research Consortium. Th

SUBMITTER: Al-Azizi K 

PROVIDER: S-EPMC12418439 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature