Rotational Motion in Bispidines: A Conformational Study.

ABSTRACT: A detailed conformational analysis of N-substituted bispidines has been performed to determine the factors governing the restricted rotational motion induced by the substituents. This investigation combines computational studies of the transition state involved in the rotation with experimental characterization of the rotamers arising from the restricted rotation.

SUBMITTER: Migliano F 

PROVIDER: S-EPMC12418502 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature