Colorectal cancer incidence after the first surveillance colonoscopy and the need for ongoing surveillance: a retrospective, cohort analysis.

ABSTRACT:

Background

Recommendations for the first postpolypectomy surveillance colonoscopy (SC1), based on stratifying postpolypectomy colorectal cancer (CRC) risk, are well established. Limited data inform recommendations for surveillance beyond SC1.

Objective

We investigated which patient groups need surveillance beyond SC1.

Design

Retrospective analysis of patients who underwent colonoscopy with polypectomy at 17 UK hospitals, mostly from 2000 to 2010, and had ≥1 surveillance colonoscopies. Cancer and death data were collected through 2017. We examined patients in groups defined by risk at baseline and SC1, applying risk definitions from the 2020 UK postpolypectomy surveillance guidelines: 'low risk, low risk' (LR-LR), 'high risk, low risk' (HR-LR), 'low risk, high risk' (L

SUBMITTER: Robbins EC 

PROVIDER: S-EPMC12418537 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature