Physical activity trajectories and accumulation over adulthood and their associations with all-cause and cause-specific mortality: a systematic review and meta-analysis.

ABSTRACT:

Objective

To understand the associations of trajectories and accumulation of physical activity (PA) over adulthood with all-cause, cardiovascular disease (CVD), and cancer mortality.

Design

Systematic review and meta-analyses.

Data sources

PubMed, Embase, Scopus, Cochrane Library, Web of Science, CINAHL, MEDLINE, SPORTDiscus, and reference lists of included studies.

Eligibility criteria

Population-based prospective studies with (1) non-clinical adult population, (2) PA assessed ≥2 timepoints as exposure, (3) all-cause, CVD or cancer mortality as outcomes with risk measures, and (4) publication up to 9 April 2024 and in English.

Results

85 studies with three main types of PA exposure (ie, trajectory, time-varying, and cumulative/average) were included. Of

SUBMITTER: Yu R 

PROVIDER: S-EPMC12418563 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature