Improving outcomes for very preterm babies in England: does place of birth matter? Findings from OPTI-PREM, a national cohort study.

ABSTRACT:

Objective

Babies born between 27⁺⁰ and 31⁺⁶ weeks of gestation contribute substantially towards infant mortality and morbidity. In England, their care is delivered in maternity services colocated with highly specialised neonatal intensive care units (NICU) or less specialised local neonatal units (LNU). We investigated whether birth setting offered survival and/or morbidity advantages to inform National Health Service delivery.

Design

Retrospective national cohort study.

Setting

LNU, NICU, England.

Patients

UK National Neonatal Research Database whole population data for births between 27⁺⁰ and 31⁺⁶ weeks of gestation, discharged from/died within neonatal units between 1 January 2014 and 31 December 2018. We linked ba

SUBMITTER: Pillay T 

PROVIDER: S-EPMC12418565 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature