Plasma transfusions in neonatal intensive care units: a prospective observational study.

ABSTRACT:

Objective

Despite lack of evidence supporting efficacy, prophylactic fresh frozen plasma and Octaplas transfusions may be administered to very preterm infants to reduce bleeding risk. International variation in plasma transfusion practices in neonatal intensive care units (NICUs) is poorly understood, therefore, we aimed to describe neonatal plasma transfusion practice in Europe.

Design

Prospective observational study.

Setting

64 NICUs in 22 European countries, with a 6-week study period per centre between September 2022 and August 2023.

Patients

Preterm infants born below 32 weeks of gestational age.

Interventions

Admission to the NICU.

Main outcome measures

Plasma transfusion prevalence, cumulative incidence, indications, transfusion volumes and

SUBMITTER: Houben NAM 

PROVIDER: S-EPMC12418581 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature