Dietary inflammatory index and the risk of colorectal adenomas and cancer: a systematic review and dose-response meta-analysis.

ABSTRACT:

Background

The potential association between dietary inflammatory index (DII) and colorectal cancer (CRC) risk, as well as colorectal adenomas (CRA) risk, has been extensively studied, but the findings remain inconclusive. We conducted this systematic review and dose-response meta-analysis to investigate the relationship between the DII and CRC and CRA.

Methods

We comprehensively searched the PubMed, Embase, Cochrane Library, and Web of Science databases for cohort and case-control studies reporting the relationship between DII and CRA, or between DII and CRC, as of 15 July 2025. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using a random-effects model. Dose-response analysis was conducted where possible. Subgroup analyses were conducted to

SUBMITTER: Wu YJ 

PROVIDER: S-EPMC12418642 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature