How COVID-19 Treatment in Pregnancy Reflects Healthcare Utilization During a Pandemic: A Two-Stage Individual Participant Data Meta-Analysis Combining Case-Based Registries.

ABSTRACT:

Purpose

To describe an international response to the COVID-19 pandemic by estimating the prevalence of medication use for COVID-19 treatment in pregnancy, stratified by hospitalization, trimester of pregnancy, and country.

Methods

We conducted a two-stage individual participant data meta-analysis of proportions from primary data on medications used to treat COVID-19 during pregnancy. A common data model was developed to pool the data from single-country and international registries. Data from pregnant individuals with COVID-19 between February 2020 and October 2022 were included in study platforms across 9 data sources. Patient information was abstracted from medical records.

Results

Among 24 937 pregnant individuals, the pooled prevalences of individuals receiving me

SUBMITTER: Maisonneuve E 

PROVIDER: S-EPMC12418691 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature