Burden and etiology of heart failure in mainland China from 1990 to 2021: Results from the GBD 2021 study.

ABSTRACT:

Background and aims

Heart failure (HF) represents a major global public health challenge. This study aims to report the HF prevalence and disability in mainland China from 1990 to 2021, as well as the underlying etiology.

Methods

Data on HF-related prevalence and years lived with disability (YLDs) were obtained from Global Burden of Disease 2021 study for mainland China. Analyses were conducted by age and sex, with the burden rates expressed per 100,000 population. Age-period-cohort models were used to describe the trajectory of HF during 1990-2021. We analyzed the potential etiologies of HF, and performed decomposition analysis to quantify the main drivers of changes in the burden.

Results

In 2021, the prevalence and YLDs rates of HF in mainland China were 920.7 per

SUBMITTER: Fang Z 

PROVIDER: S-EPMC12418866 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature