The prevalence and role of human metapneumovirus in respiratory tract infections: a systematic review and meta-analysis of global data.

ABSTRACT:

Background

Human metapneumovirus (hMPV) is a significant respiratory pathogen, yet its global prevalence and epidemiological patterns remain poorly characterized. This study presents the first comprehensive systematic review and meta-analysis of hMPV prevalence among patients with respiratory tract infections (RTIs), addressing a critical gap in the literature, and clarifying the association between hMPV infection and RTIs.

Methods

We conducted a systematic search across PubMed, Scopus, and Web of Science, from 2002 to 2024. Studies reporting hMPV prevalence detected by Polymerase chain reaction-based methods in respiratory samples were included. Data was analyzed using random-effects models, with subgroup analyses by age, region, diagnostic methods, and patient's demographi

SUBMITTER: Khales P 

PROVIDER: S-EPMC12418874 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature