Three-dimensional, patient-specific simulation of cerebral blood flow velocities as a new approach for individualized stroke prevention and treatment.

ABSTRACT:

Background

Three-dimensional simulations of cerebral blood flow are a highly promising approach for individualized diagnostics and therapy planning in cerebrovascular disease. The aim of this study is to validate simulated blood flow velocities generated by a patient-specific model using the innovative Stroke Quantification software (StroQ, ELPIS Simulation GmbH, Germany).

Methods

In this study, consecutive patients with transient ischemic attack (TIA) or minor ischemic stroke (defined as NIHSS ≤ 4) treated at a tertiary stroke center have been investigated. The patients underwent both computed tomography angiography (CTA) and neurovascular ultrasound (nvUS) of the extra- and intracranial arteries. Patients with relatively large artery atherosclerosis (LAA) such as significa

SUBMITTER: Leyhe JR 

PROVIDER: S-EPMC12419103 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature