Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): About three case reports.

ABSTRACT:

Background

Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), is an extremely rare and aggressive ovarian cancer affecting young women, typically associated with poor survival. We present three cases of SCCOHT and review the current literature regarding clinical features, diagnosis, management, and survival.

Cases

Three patients aged 16, 29, and 39 years were treated for ovarian masses. None presented with hypercalcemia. In case 1, MRI findings mimicked a mucinous cystadenocarcinoma, while the other two cases appeared as benign ovarian tumors. Following initial surgery and histological diagnosis of SCCOHT, all patients received comprehensive radical surgery, multi-agent chemotherapy, radiotherapy, and autologous stem cell transplantation. Two patients remain rec

SUBMITTER: Benichou J 

PROVIDER: S-EPMC12419111 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature