Antithrombotic therapy after cardiac valve surgery: prospective real-world data of Class II guidelines application and outcomes from the EURObservational Research Programme Valvular Heart Disease II survey.

ABSTRACT:

Background

Antithrombotic therapy (AT) after cardiac valve surgery is complex, with guidelines often relying on limited evidence.

Objectives

This study examines real-world adherence to the European Society of Cardiology Class II, level C recommendations for AT in valve surgery, as well as the 6-month impact of AT on patient outcomes.

Methods

This prospective, observational subanalysis of the European Society of Cardiology EURObservational Research Programme Valvular Heart Disease II survey included 6 substudies examining different valve interventions and AT regimens. Patient demographics, clinical characteristics, and 6-month outcomes were compared between groups receiving the recommended AT and those who did not.

Results

Guideline adherence varied widely (39.5

SUBMITTER: Roosens B 

PROVIDER: S-EPMC12419113 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature