Investigating the relationship between psoriasis and venous thromboembolism using systematic review, meta-analysis and Mendelian randomization study.

ABSTRACT:

Background

Numerous studies have investigated the correlation between psoriasis and venous thromboembolism (VTE). However, the findings have not been entirely conclusive. The objective of this study was to assess the association between psoriasis and the risk of VTE by conducting a systematic review and meta-analysis, complemented by Mendelian randomization (MR) analysis to evaluate potential causality.

Methods

In our study, we utilize meta-analysis and MR to delve into the potential relationship between psoriasis and VTE. A comprehensive literature search was conducted across PubMed, Web of Science, and Embase. Different measures of association reported in the original studies - including relative risks (RRs), hazard ratios (HRs), standardized incidence ratios (SIRs), and o

SUBMITTER: Yang M 

PROVIDER: S-EPMC12419365 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature