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Combined Particulated Juvenile Articular Cartilage Allograft Transplantation With Autogenous Bone Graft for Symptomatic Osteochondral Defects in the Tibial Plateau.


ABSTRACT: Osteochondral lesions of the tibial plateau are rare, comprising only 1% to 2% of knee osteochondritis dissecans cases. Due to their rarity and challenging anatomic location, standardized treatment guidelines remain undefined. We describe a surgical technique combining autogenous bone grafting with particulated juvenile articular cartilage allograft (DeNovo NT; Zimmer Biomet). The advantages of this method include single-stage management, the presence of biologically active juvenile chondrocytes promoting robust hyaline-like cartilage, simultaneous restoration of subchondral bone defects, and enhanced surgical access to an anatomically challenging site.

SUBMITTER: Walker PB 

PROVIDER: S-EPMC12420580 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature