The utility of long-term methylphenidate in preserving intellectual development in survivors of childhood brain tumour.

ABSTRACT:

Background

Survivors of childhood brain tumour face significant neurocognitive late effects, including impairment in processing speed and attention. Deficits to these core cognitive domains contribute to the plateauing of age-appropriate intellectual development as the child matures. While short-term studies demonstrate the utility of methylphenidate in enhancing processing speed and attention during early recovery, its longer-term role in sustaining intellectual development remains underexplored.

Methods

The current study examined the long-term effects of methylphenidate on intellectual development in 23 survivors of childhood brain tumour, matched on multiple clinical and demographic variables against 23 controls. Intellectual assessments were conducted at baseline and aft

SUBMITTER: Hagan AJ 

PROVIDER: S-EPMC12420733 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature