Atrial Fibrillation Recurrence Reduction: What Treatments Work Best Postablation? A Network Meta-Analysis.

ABSTRACT:

Background

Atrial fibrillation (AF) is the most common cardiac arrhythmia, associated with significant morbidity, including increased risks of stroke, heart failure, and mortality. While catheter ablation is an effective rhythm control strategy, high recurrence rates postprocedure remain a major clinical challenge. Inflammation plays a key role in AF pathogenesis, and anti-inflammatory therapies have emerged as potential adjunctive treatments to reduce recurrence. This study provides the first network meta-analysis evaluating the efficacy of anti-inflammatory therapies in preventing AF recurrence postablation.

Methods

A systematic review and network meta-analysis were conducted in accordance with PRISMA-NMA guidelines. Randomized controlled trials examining the effects of co

SUBMITTER: Jaroonpipatkul S 

PROVIDER: S-EPMC12420840 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature