Effectiveness and Safety of Intramyocardial Needle Ablation for Refractory Ventricular Tachycardia and Premature Ventricular Complexes: A Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction

Intramyocardial needle ablation is a novel technique for treating refractory ventricular tachycardia (VT) and premature ventricular complexes (PVC). However, studies defining the effectiveness and safety of this procedure are limited. This meta-analysis aims to evaluate the safety and effectiveness of needle ablation for VT and PVC refractory to standard ablation.

Methods

Embase, Ovid (includes Medline), and ClinicalTrials.gov were searched from inception to December 31, 2024. Human studies on needle ablation for recurrent VT and PVC were included. Primary outcome was immediate effectiveness (no immediate post-procedural inducible VT or PVC). Secondary outcomes were long-term effectiveness (no clinical VT or PVC at 6 months) and safety (composite measure of peri

SUBMITTER: Gupta K 

PROVIDER: S-EPMC12420884 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature