Association Between Women's Birth Weight and Reproductive Characteristics in Adulthood: The JPHC-NEXT Study.

ABSTRACT:

Background

We aimed to investigate the association between women's birth weight and their reproductive characteristics.

Methods

We used data from the Japan Public Health Center-based Prospective Study for the Next Generation (JPHC-NEXT), a population-based cohort in Japan. The main analysis included 40,796 women aged 40 to 68 years. Outcomes of interest were age at menarche, age at menopause, history of menstrual irregularity, and nulliparity. Associations between self-reported birth weight categories and outcomes were assessed using either a linear regression or a modified Poisson regression adjusted for potential confounders.

Results

Among participants with complete data, those with lower birth weights (<1,500 g and 1,500-2,499 g) compared to women with a birth weig

SUBMITTER: Itoi S 

PROVIDER: S-EPMC12420951 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature