Understanding brain donation decisions: Predictors of indecision and change over time from the Cleveland Alzheimer's Disease Research Center.

ABSTRACT:

Introduction

Little is known about factors influencing indecision or changes in brain donation program (BDP) enrollment status among Alzheimer's disease and related dementias research participants. This study examined demographic features associated with these decisions in participants from the Cleveland Alzheimer's Disease Research Center (CADRC).

Methods

Demographics and BDP status were extracted from the CADRC database and analyzed based on initial and current BDP enrollment status.

Results

At baseline, BDP enrollees were more likely to be older, cognitively impaired, White, partnered, have more years of education, and have a relative or partner serving as a study partner. Participants who changed BDP status over time were more often cognitively unimpaired and had

SUBMITTER: Powell L 

PROVIDER: S-EPMC12421064 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature