Early postoperative pain and 30-day complications following major abdominal surgery: a retrospective cohort study.

ABSTRACT:

Background

Increasing evidence supports a positive relationship between the intensity of early postoperative pain, and the risk of 30-day postoperative complications. Higher pain levels may hamper recovery and contribute to immunosuppression after surgery. This leaves patients at risk of postoperative complications.

Methods

One thousand patients who underwent major abdominal surgery (cytoreductive surgery and hyperthermic intraperitoneal chemotherapy, esophageal, liver, or pancreas surgery) at the Radboud university medical center were randomly selected from eligible patients between 2014 and 2020. Pain scores on day 1, the independent variable of interest, were extracted from the electronic patient files. Outcome measures were 30-day postoperative complications (infectious,

SUBMITTER: Helden EV 

PROVIDER: S-EPMC12421097 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature