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Early Invasive Strategy in Non-ST-Elevation Acute Coronary Syndrome With Congestive Heart Failure - A Systematic Review and Meta-Analysis.


ABSTRACT:

Background

Congestive heart failure (CHF) is associated with worse clinical outcomes in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS); however, the optimal timing of invasive intervention in NSTE-ACS with CHF remains unclear. In this study, we assessed the impact of early vs. delayed invasive strategies on mortality and cardiac events by synthesizing a systematic review of randomized controlled trials of patients with NSTE-ACS.

Methods and results

We searched MEDLINE, CENTRAL, and the Web of Science for randomized controlled trials comparing early and delayed invasive strategies in patients with NSTE-ACS and CHF, published before February 2023. Observational studies were excluded. The primary endpoint was a composite of all-cause mortality and myocardial

SUBMITTER: Hao K 

PROVIDER: S-EPMC12421134 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature