Priorities for Early Revascularization or Introduction of Mechanical Circulatory Support in Patients With Acute Coronary Syndrome Complicated by Cardiogenic Shock　- A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

The optimal timing for mechanical circulatory support (MCS) initiation in patients with acute myocardial infarction complicated by cardiogenic shock (CS) is unknown, so in this study we analyzed whether MCS implementation before percutaneous coronary intervention (PCI) is associated with better outcomes compared to after PCI.

Methods and results

We conducted a systematic review and meta-analysis using a random-effects model to account for potential heterogeneity. Risk ratios and 95% confidence intervals were used for dichotomous outcomes. PubMed, Web of Science, and CENTRAL were searched up to April 30, 2023. Certainty of evidence was evaluated according to the Risk of Bias in Non-Randomized Studies of Interventions-I tool. A total of 14 observational studies met

SUBMITTER: Katasako-Yabumoto A 

PROVIDER: S-EPMC12421136 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature