High-sensitivity troponin T as a rule-out marker for myocardial inflammation detectable by CMR imaging.

ABSTRACT:

Background

Acute myocarditis is a potentially life-threatening cardiac condition and immediate assessment of this disease is imminent. While laboratory tests, electrocardiography or transthoracic echocardiography can provide indirect signs for the presence of acute myocarditis, cardiac magnetic resonance (CMR) imaging enables direct visualisation of myocardial inflammation and confirms the diagnosis.Since there is limited accessibility to CMR, the goal of this study was to evaluate the sensitivity and specificity of an elevation of established biomarkers for the diagnosis of myocarditis and to define a specific rule-out threshold for deferring CMR.

Methods

244 consecutive patients with clinical suspicion of acute myocarditis underwent comprehensive CMR imaging. CMR data and

SUBMITTER: Puetz A 

PROVIDER: S-EPMC12421164 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature