Measuring alignment between the ADRC UDS data elements, FDA, and EHR data standards.

ABSTRACT:

Introduction

We compared and measured alignment between the Health Level Seven (HL7) Fast Healthcare Interoperability Resources (FHIR) standard used by electronic health records (EHRs), the Clinical Data Interchange Standards Consortium (CDISC) standards used by industry, and the Uniform Data Set (UDS) used by the Alzheimer's Disease Research Centers (ADRCs).

Methods

The ADRC UDS, consisting of 5959 data elements across eleven packets, was mapped to FHIR and CDISC standards by two independent mappers, with discrepancies adjudicated by experts.

Results

Forty-five percent of the 5959 UDS data elements mapped to the FHIR standard, indicating possible electronic obtainment from EHRs. Ninety-four percent mapped to the CDISC standards, demonstrating high compatibility with

SUBMITTER: Wang Z 

PROVIDER: S-EPMC12421241 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature