Left Atrial Appendage Occlusion vs Anticoagulants in Dialysis With Atrial Fibrillation.

ABSTRACT:

Importance

Patients with kidney failure (KF) receiving long-term dialysis have increased incidence of atrial fibrillation (AF). Patients with KF and AF have increased risk of stroke, death, and bleeding compared with age-matched cohorts. In KF, the use of oral anticoagulants (OACs) increases hemorrhage risk, offsetting potential benefits and making left atrial appendage occlusion (LAAO) a potentially promising solution for risk reduction in AF.

Objectives

To compare the outcomes and safety of OACs and LAAO for risk reduction of AF in patients with KF.

Design, setting, and participants

This retrospective cohort study assessed patients with KF enrolled in the US Renal Data System registry between January 1, 2015, and December 31, 2018, who were diagnosed with AF after i

SUBMITTER: Dhar G 

PROVIDER: S-EPMC12421340 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature