Wearable device-measured circadian rest-activity rhythm with mortality risk in patients with cancer.

ABSTRACT:

Objectives

The objectives were to examine the associations between accelerometer-measured circadian rest-activity rhythm (CRAR), the most prominent circadian rhythm in humans and the risk of mortality from all-cause, cancer and cardiovascular disease (CVD) in patients with cancer.

Methods

7456 cancer participants from the UK Biobank were included. All participants wore accelerometers from 2013 to 2015 and were followed up until 24 January 2024, with a median follow-up of 9.00 years. The multidimensional parameters of the CRAR were calculated using the 7-day accelerometer data collected under free-living conditions. Cox proportional hazard models were used to evaluate the associations between CRAR and all-cause, cancer and CVD mortality.

Results

Among 7456 cancer patie

SUBMITTER: Mei X 

PROVIDER: S-EPMC12421596 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature