<i>Th</i>IPK1 regulates lignocellulolytic enzyme expression during wood degradation in white-rot fungi.

ABSTRACT: White-rot fungi play a crucial role in terrestrial carbon cycling by decomposing lignocellulose, particularly lignin, in plant cell walls. The degradation process is initiated by the fungal perception of lignocellulosic signals, which trigger a complex regulatory network controlling lignocellulolytic enzyme expression. However, the ecological and molecular mechanisms underlying how these fungi sense lignocellulosic signals and regulate their degradation capacity remain unclear. In this study, a degenerated Trametes hirsuta AH28-2 that lost lignocellulolytic degradation capacity was generated through successive subcultures. Phenotypic stability, transcriptomic analyses, and functional validation revealed that ThIPK1, a key gene in the inositol polyphosphate pathway, regulates

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12421882 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature