PmeR, a TetR-like transcriptional regulator, is involved in both auxin signaling and virulence in the plant pathogen <i>Pseudomonas syringae</i> strain <i>Pto</i>DC3000.

ABSTRACT: Plant pathogenic bacteria, such as Pseudomonas syringae strain PtoDC3000, respond to host signals through complex signaling networks that regulate bacterial growth and virulence. The plant hormone indole-3-acetic acid (IAA), also known as auxin, promotes bacterial pathogenesis via multiple mechanisms, including through reprogramming of bacterial transcription. However, the mechanisms that PtoDC3000 uses to sense and respond to auxin are not well understood. Here, we identify a novel bacterial auxin-signaling mechanism mediated by pmeR, which encodes a TetR-like family transcriptional repressor that acts as an important regulator of IAA-responsive gene expression in PtoDC3000. Using qRT-PCR and transcriptional reporter assays, we show that pmeR is i

SUBMITTER: Lee C-Y 

PROVIDER: S-EPMC12421961 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature