Coffee intake and the vasopressin system: an epidemiological and experimental study.

ABSTRACT: Coffee is epidemiologically linked to health benefits and risks. Coffee is thought to be a diuretic. However, it can still contribute to daily fluid intake. Vasopressin is the most important physiological regulator of body fluid balance and diuresis. This study aimed to map the effects of coffee intake on vasopressin concentration. In the population-based cross-sectional Malmö Offspring Study (n = 3,270, age 18-75 years, 47% males) we performed linear regression analyses to investigate the association between coffee intake and plasma concentration of copeptin (a vasopressin surrogate marker). Coffee intake was assessed using a 4-day food record. Moreover, we compared plasma copeptin concentrations after intake of 4 dL of coffee and 10 mL of water (control) in an experimental study (n = 26,

SUBMITTER: Schill F 

PROVIDER: S-EPMC12421983 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature