In Vivo Study of Bone Growth Around Additively Manufactured Implants With Ti-6Al-4V and Bioactive Glass Powder Composites.

ABSTRACT: Effective osseointegration is a fundamental requirement in biomedical implant applications. Additive manufacturing allows precise control over implant geometry and material composition, enhancing implant design flexibility. Bioactive glass (BG) can substantially enhance bone binding and bioactivity; however, limited research has been conducted on its incorporation into additively manufactured implants. The performance of BG varies depending on the incorporation method, and the spatial and temporal evolution of its integration remains unclear. In this study, we synthesized Ti-6Al-4V/58S BG composites by using the selective laser melting method and systematically compared the effects of BG coating and doping in additively manufactured implants. In vivo histological results from animal tests

SUBMITTER: Lee CY 

PROVIDER: S-EPMC12422175 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature