A low-cost cellulose-based composite as an efficient solid phase extraction sorbent for the determination of antibiotics in water.

ABSTRACT: Pharmaceutical pollutants in water pose significant environmental and public health risks, particularly in regions with limited monitoring capabilities. This study presents a low-cost, cellulose-based solid-phase extraction (SPE) adsorbent (C/PVPP/MDI) for the determination of five antibiotics: tetracycline (TET), ampicillin (AMP), sulfamethoxazole (SMX), penicillin V (PEN V), and chloramphenicol (CAP) in water. The adsorbent was synthesized by cross-linking cellulose with poly(vinyl-polypyrrolidone) (PVPP) and 4,4-methylenebisphenyldiisocyanate (MDI). It exhibited excellent analytical performance with low detection limits (0.03-2.07 ng L^-1), strong linearity (R ² > 0.99), and high recoveries (84.8-97.6%) in both tap and river water, comparable to a commercial

SUBMITTER: Olorunnisola D 

PROVIDER: S-EPMC12422246 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature