Macular Optical Coherence Tomography Parameters and Incident Glaucoma Among Myopic Eyes.

ABSTRACT:

Purpose

The purpose of this study was to estimate the correlations between macular optical coherence tomography (OCT)-derived metrics and incident glaucoma risk in myopic eyes.

Methods

This longitudinal observational study included 24,181 individuals with myopia (spherical equivalence [SE] ≤ -0.5 diopters [D]) from the UK Biobank study.

Results

Participants (mean age = 55.5 ± 8.0 years, 54.5% women) were followed up for 13.2 ± 1.2 years and incident glaucoma was diagnosed in 582 eyes. Those who developed glaucoma were significantly older (P < 0.001), more likely to be male participants (P < 0.001), and had more pronounced myopic refractive error (P < 0.001). Cox regression analyses indicated that participants with thinner retinal nerve fiber layer (RNFL; hazard ratio

SUBMITTER: Ma W 

PROVIDER: S-EPMC12422395 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature