Self-Assembled Cysteamine Reporter Ligands for SERS Nitrate Detection in Continuous Flow.

ABSTRACT: Elevated nitrate concentrations in aquatic environments can contribute to the formation of harmful algal blooms, which lead to eutrophication. In this work, cysteamine self-assembled monolayers (SAMs) on two-dimensional gold nanostructured substrates were investigated for the capture and detection of nitrate anions by surface enhanced Raman scattering (SERS) under continuous fluid flow. An indirect detection strategy is demonstrated where cysteamine Raman activity and SAM reconfiguration change due to nitrate adsorption. Nitrate adsorption, as well as SAM reconfiguration based on the gauche to trans conformation ratio, were dependent upon the cysteamine protonation state. The terminating amine of cysteamine was Raman active when protonated near the expected SAM pK

SUBMITTER: Kuster T 

PROVIDER: S-EPMC12422535 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature