Changing cognitive chimera states in human brain networks with age: Variations in cognitive integration and segregation.

ABSTRACT: Although the brain's structural and functional alterations with age are individually well documented, how differences in cognitive abilities emerge from variations in the underlying spatio-temporal patterns of regional brain activity is largely unknown. Patterns of increased synchronization between brain regions are taken as enhanced cognitive integration, while decreased synchronization is indicative of cognitive segregation. The ability to dynamically switch between different levels of integration and segregation across different cognitive systems is believed to be crucial for overall cognitive performance. Building on a recently proposed cognitively informed, synchronization-based framework, we study here age-related variations in dynamical flexibility between segregation and integratio

SUBMITTER: Patton A 

PROVIDER: S-EPMC12422585 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature