Physical activity and mobility disability in older adult cancer survivors.

ABSTRACT:

Background

Cancer survivors may be more likely to experience accelerated declines in physical function compared to cancer-free controls, but objective data and knowledge of preventive interventions are limited.

Methods

The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, single-blinded, randomized trial conducted at 8 centers across the United States that enrolled 1635 sedentary adults aged 70-89 years and with physical limitations but who could walk 400 m at baseline, of which 371 (22.7%) reported a history of cancer. Participants were randomized in a 1:1 ratio to a health education or physical activity program. The primary endpoint was time to major mobility disability, defined objectively by the inability to walk 400 m in less than 15 mi

SUBMITTER: Brown JC 

PROVIDER: S-EPMC12422780 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature