Potential gains from radical treatment of men with prostate cancer according to life expectancy.

ABSTRACT:

Objectives

To investigate the impact of age and life expectancy on treatment decisions and its consequences for outcomes among men with intermediate and high-risk prostate cancer (PCa).

Materials and methods

We studied men in Prostate Cancer data Base Sweden (PCBaSe) diagnosed between 2008 and 2022 with intermediate-risk or high-risk localized or locally advanced PCa and life expectancy between 2.5 and 15 years in the absence of PCa. Estimates of life expectancy were based on age and two comorbidity indices.

Results

A total of 32 196 men were included in the analyses. Of these, 17 419 (54%) had a life expectancy between 10 and 15 years, of whom 11 147 (64%) received primary radical treatment. Age had a stronger influence than life expectancy on the selection of treatm

SUBMITTER: Irenaeus S 

PROVIDER: S-EPMC12422882 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature