A haplotype-resolved pangenome of the barley wild relative Hordeum bulbosum.

ABSTRACT: Wild plants can contribute valuable genes to their domesticated relatives¹. Fertility barriers and a lack of genomic resources have hindered the effective use of crop-wild introgressions. Decades of research into barley's closest wild relative, Hordeum bulbosum, a grass native to the Mediterranean basin and Western Asia, have yet to manifest themselves in the release of a cultivar bearing alien genes². Here we construct a pangenome of bulbous barley comprising 10 phased genome sequence assemblies amounting to 32 distinct haplotypes. Autotetraploid cytotypes, among which the donors of resistance-conferring introgressions are found, arose at least twice, and are connected among each other and to diploid forms through gene flow. The differential amplification of transpos

SUBMITTER: Feng JW 

PROVIDER: S-EPMC12422954 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature