Pharmacist-assisted implementation of guideline recommendations for QTc monitoring during psychopharmacotherapy - a prospective, randomized feasibility study.

ABSTRACT:

Introduction

Many psychotropic drugs potentially prolong the QTc interval. The aim of this study was to investigate the feasibility of the pharmacist-supported implementation of a new local guideline for QTc monitoring at a psychiatric department and to gather preliminary data on the effectiveness of this intervention.

Methods

The study was conducted as a prospective, randomized-controlled feasibility study at the inpatient service of a department of psychiatry. In the intervention group (IG), guideline-based monitoring of QTc intervals was supported by a clinical pharmacist. The control group (CG) was solely monitored by the treating physicians. The primary effectiveness outcome was the mean change in the QTc interval between admission (T₀) and 30 days after admi

SUBMITTER: Wien K 

PROVIDER: S-EPMC12423074 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature