Outcomes of the management of synchronous rectal and prostate cancer: a systematic review.

ABSTRACT:

Background

The optimal management of synchronous rectal cancer (RC) and prostate cancer (PC) remains unclear. This systematic review evaluates treatment strategies and reports postoperative, oncological, and quality-of-life outcomes in patients treated with curative intent.

Methods

Following PRISMA guidelines, this systematic review was registered in PROSPERO (CRD42024598049). A search of Ovid MEDLINE, Embase, CENTRAL, and CDSR (inception to February 2025) identified randomised controlled trials and observational studies on synchronous RC and PC. Synchronous disease was defined as diagnosis or treatment initiation within 12 months. Patients with incurable RC were excluded. Treatment strategies and surgical approaches were analysed, with postoperative, oncological, and surviv

SUBMITTER: Nassar A 

PROVIDER: S-EPMC12423125 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature