Compositional analysis of the association between 24 h movement behaviours, HbA_1c and interstitial glucose in children and adolescents with type 1 diabetes mellitus: a two-year longitudinal analysis of the Diactive-1 cohort study.

ABSTRACT:

Aims/hypothesis

The aim of this study was to examine the association of physical activity, sedentarism and sleep with HbA_1c and interstitial glucose in children and adolescents with type 1 diabetes through a 24 h compositional analysis.

Methods

The study involved 83 young people diagnosed with type 1 diabetes (aged 6-18 years; 45% girls, mean HbA_1c 57.54 ± 9.22 mmol/mol (7.4 ± 0.8%); median interstitial glucose 9.37 mmol/l [IQR 8.68-10.31]) from the Diactive-1 cohort study, followed up for 2 years. A triaxial accelerometer was used to objectively measure 24 h movement behaviours for 9 days. HbA_1c levels were obtained from medical records, and interstitial glucose data were collected through continuous glucose monitoring. Linear mixed models w

SUBMITTER: Munoz-Pardeza J 

PROVIDER: S-EPMC12423199 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature