Association of maternal overweight and gestational diabetes mellitus with offspring adiposity trajectory: from birth to early adolescence.

ABSTRACT:

Aims/hypothesis

We aimed to examine offspring adiposity trajectories from birth to age 9-14 years and to assess the joint associations of maternal overweight and gestational diabetes mellitus (GDM) with these trajectories.

Methods

This is a prospective cohort study with 564 mother-child dyads from the Hyperglycemia and Adverse Pregnancy Outcome study Hong Kong field centre. Assessments and anthropometric measurements were taken during pregnancy, at delivery and at median ages of 7 and 10 years postpartum. Offspring adiposity was primarily assessed using sum of skinfold thickness. We used linear mixed-effect models to evaluate the independent and joint associations of maternal overweight and GDM with the offspring adiposity trajectories, and applied group-based trajectory mod

SUBMITTER: Deng Y 

PROVIDER: S-EPMC12423264 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature