Fat-soluble vitamins as biomarkers of nutritional status and their relation with complications in polytrauma patients.

ABSTRACT: Background and AimsThis exploratory observational prospective study aimed to evaluate fat-soluble vitamin plasma levels during hospital admission and its relation with the development of malnutrition and complications in polytrauma patients, considering the protocolized multivitamin supplementation during intensive care unit (ICU) admission.MethodsIn 49 well-nourished polytrauma (injury severity score ≥ 16) patients admitted to the ICU of two level-1 trauma centers, vitamin A, D, and E levels were assessed weekly during hospital stay. All patients received multivitamin supplementation during ICU stay. Linear mixed-effect models were used to assess a trend in vitamin levels over time during hospital stay. Mixed-effects logistic regression analysis was performed to relate vitamin concentrati

SUBMITTER: Verheul EAH 

PROVIDER: S-EPMC12423471 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature