Determining the optimal portal pressure gradient after small-diameter TIPS for ascites: a retrospective study.

ABSTRACT:

Background

The optimal hemodynamic threshold for portal pressure gradient (PPG) following transjugular intrahepatic portosystemic shunt (TIPS) for ascites remains uncertain.

Objective

This study aimed to elucidate the relationship between post-TIPS PPG and clinical outcomes in patients undergoing small-diameter (8-mm) TIPS for ascites.

Design

Single-center retrospective study.

Methods

From June 2015 to June 2023, consecutive patients receiving small-diameter (8-mm) TIPS for refractory or recurrent ascites were considered for inclusion retrospectively. The impact of PPG on clinical outcomes-including ascites response, overt hepatic encephalopathy (OHE), further decompensation, and mortality-was evaluated using Fine and Gray competing risk regression models, both

SUBMITTER: Liu G 

PROVIDER: S-EPMC12423538 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature