Predictors of Anorexia Nervosa and Obsessive-Compulsive Disorder Comorbidity and Order of Diagnosis in a Danish National Cohort.

ABSTRACT:

Objective

Anorexia nervosa (AN) and obsessive-compulsive disorder (OCD) are highly comorbid; however, limited research has examined etiological pathways specific to individuals with AN developing OCD or individuals with OCD developing AN. This exploratory study aimed to identify factors influencing AN-OCD comorbidity with a focus on the order of diagnosis.

Method

Using Danish national registers, 6449 individuals with AN and 9352 individuals with OCD were examined to assess the risk of subsequent OCD and AN. Explored predictors included parental characteristics, birth characteristics, childhood adversity, autoimmune and autoinflammatory diseases, psychiatric disorders, and prescriptions. Hazard ratios (HR) were calculated using Cox regression. Parallel analyses were conducted

SUBMITTER: Zhu LY 

PROVIDER: S-EPMC12423569 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature