Adverse Childhood Experiences, Neurocognitive Functions, and Long-Term Mortality Risk.

ABSTRACT:

Importance

Higher intellectual abilities have been associated with lower mortality risk in several longitudinal cohort studies. However, these studies did not fully account for early life contextual factors or test whether the beneficial associations between higher neurocognitive functioning and mortality extend to children exposed to early adversity.

Objective

To explore how the associations of child neurocognition with mortality changed according to the patterns of adversity children experienced.

Design, setting, and participants

The Collaborative Perinatal Project (CPP) is a US pregnancy cohort study conducted at 12 US academic medical centers among children born between 1959 and 1966. Pregnant women at participating centers were invited to enroll in the study, and

SUBMITTER: Yu J 

PROVIDER: S-EPMC12423876 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature